PD-1+ natural killer cells in human non-small cell lung cancer can be activated by PD-1/PD-L1 blockade
Marcel P. Trefny, Monika Kaiser, Michal A. Stanczak, Petra Herzig, Spasenija Savic, Mark Wiese, Didier Lardinois, Heinz Läubli, Franziska Uhlenbrock, Alfred Zippelius
Topics & Concepts
Interleukin 21BlockadeImmune checkpointCancer researchLymphokine-activated killer cellImmune systemInterleukin 12Cytotoxic T cellImmunotherapyPD-L1Immunological synapseBiologyImmunologyReceptorT cellIn vitroT-cell receptorBiochemistryImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersCAR-T cell therapy research