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Recent advances in discovery and biosynthesis of natural products from myxobacteria: an overview from 2017 to 2023

Chaoyi Wang, Jia-Qi Hu, Degao Wang, Yue‐zhong Li, Changsheng Wu

2024Natural Product Reports20 citationsDOI

Abstract

Covering: 2017.01 to 2023.11Natural products biosynthesized by myxobacteria are appealing due to their sophisticated chemical skeletons, remarkable biological activities, and intriguing biosynthetic enzymology. This review aims to systematically summarize the advances in the discovery methods, new structures, and bioactivities of myxobacterial NPs reported in the period of 2017-2023. In addition, the peculiar biosynthetic pathways of several structural families are also highlighted.

Topics & Concepts

MyxobacteriaComputational biologyDrug discoveryBiologyChemistryBioinformaticsGeneticsBacteriaMicrobial Natural Products and BiosynthesisMarine Sponges and Natural ProductsMicrobial Metabolism and Applications