Non-Alcoholic Fatty Liver Disease and Cardiovascular Comorbidities: Pathophysiological Links, Diagnosis, and Therapeutic Management
Alexandra Jichitu, Simona Bungău, Ana Maria Alexandra Stănescu, Cosmin Mihai Vesa, Mirela Mărioara Toma, Cristiana Bustea, Stela Iurciuc, Marius Rus, Nicolae Bacalbaşa, Camelia Cristina Diaconu
Abstract
Non-alcoholic fatty liver disease (NAFLD) has a growing prevalence in recent years. Its association with cardiovascular disease has been intensively studied, and certain correlations have been identified. The connection between these two entities has lately aroused interest regarding therapeutic management. In order to find the best therapeutic options, a detailed understanding of the pathophysiology that links (NAFLD) to cardiovascular comorbidities is needed. This review focuses on the pathogenic mechanisms that are behind these two diseases and on the therapeutic management available at this time.