Chronic neuronal excitation leads to dual metaplasticity in the signaling for structural long-term potentiation
Hiromi Ueda, Yutaro Nagasawa, Aiko Sato, Maki Onda, Hideji Murakoshi
Abstract
influx and CaMKII signaling). This dual inhibition mechanism may contribute to robust neuronal protection in excitable environments.
Topics & Concepts
Long-term potentiationNeuroscienceGlutamate receptorSynaptic plasticityOptogeneticsChemistryMetaplasticityNMDA receptorStimulationLTP inductionHippocampal formationReceptorBiologyBiochemistryNeuroscience and Neuropharmacology ResearchPhotoreceptor and optogenetics researchRetinal Development and Disorders