Synthesis, biological evaluation, and molecular docking analysis of novel linker-less benzamide based potent and selective HDAC3 inhibitors
Ganesh Routholla, Sravani Pulya, Tarun Patel, Sk. Abdul Amin, Nilanjan Adhikari, Swati Biswas, Tarun Jha, Balaram Ghosh
Topics & Concepts
HDAC3ChemistryBenzamideHistone deacetylaseAcetylationDocking (animal)StereochemistryIn vitroCell cycle checkpointCell cycleBiochemistryApoptosisHistoneNursingGeneMedicineHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsPeptidase Inhibition and Analysis