TRIM21 overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma.
Zhipeng Zhao, Yuqi Wang, Dapeng Yun, Qilin Huang, Delong Meng, Qing Li, Pingzhao Zhang, Chenji Wang, Hongyan Chen, Daru Lu
Abstract
-Gal activity assay, and Cell Counting Kit-8 (CCK-8) assay. These results indicated that TRIM21 is a novel regulator in the diagnosis, prognosis, and therapy of gliomas.
Topics & Concepts
GliomaDownregulation and upregulationCancer researchCell growthCell cycleRegulatorCellSenescenceBiologyCell biologyGeneGeneticsBiochemistryinterferon and immune responsesMicroRNA in disease regulationCircular RNAs in diseases