Xanthoceraside administration produces significant antidepressant effects in mice through activation of the hippocampal BDNF signaling pathway
Wei Guan, Jianghong Gu, Chun-Hui Ji, Yue Liu, Wenqian Tang, Yao Wang, Bo Jiang
Topics & Concepts
Behavioural despair testTail suspension testAntidepressantNeurotrophic factorsPharmacologyBrain-derived neurotrophic factorNeurogenesisHippocampal formationNeuroprotectionHippocampusMedicinePsychologyInternal medicineNeuroscienceReceptorStress Responses and CortisolNerve injury and regenerationNeurogenesis and neuroplasticity mechanisms