Synthesis of a novel series of (Z)-3,5-disubstituted thiazolidine-2,4-diones as promising anti-breast cancer agents
Hussein El‐Kashef, Gamal Badr, Nagwa Abo El‐Maali, Douaa Sayed, Patricia Melnyk, Nicolas Lebègue, Rofida Abd El-Khalek
Topics & Concepts
Breast cancerApoptosisProtein kinase BChemistryCancer researchCancerFlow cytometryWestern blotPI3K/AKT/mTOR pathwayCancer cellMTT assayCell growthMolecular biologyInternal medicineBiochemistryBiologyMedicineGeneSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsSynthesis and Reactions of Organic Compounds