Self-propelling bacteria-based magnetic nanoparticles (BacMags) for targeted magnetic hyperthermia therapy against hypoxic tumors
Tashmeen Kaur, Deepika Sharma
Abstract
anti-cancer response was validated in a syngeneic xenograft model with a 50% tumor inhibition rate within 20 days and a complete tumor regression within 30 days. This proof-of-concept study demonstrates the potential of utilizing anaerobic bacteria for the delivery of magnetic nanocarriers as a smart therapeutic approach for enhanced MHCT.
Topics & Concepts
Magnetic hyperthermiaHyperthermiaNanocarriersMagnetotactic bacteriaMagnetic nanoparticlesBacteriaCancer therapyMaterials scienceHypoxia (environmental)NanoparticleCancer researchNanotechnologyMedicineChemistryCancerBiologyOxygenInternal medicineGeneticsOrganic chemistryCancer Research and TreatmentsNanoplatforms for cancer theranosticsMicro and Nano Robotics