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Diacylglyceryl-N,N,N-trimethylhomoserine-dependent lipid remodeling in a green alga, Chlorella kessleri

Yutaro Oishi, Rie Otaki, Yukari Iijima, Eri Kumagai, Motohide Aoki, Mikio Tsuzuki, Shoko Fujiwara, Norihiro Sato

2022Communications Biology57 citationsDOIOpen Access PDF

Abstract

Membrane lipid remodeling contributes to the environmental acclimation of plants. In the green lineage, a betaine lipid, diacylglyceryl-N,N,N-trimethylhomoserine (DGTS), is included exclusively among green algae and nonflowering plants. Here, we show that the green alga Chlorella kessleri synthesizes DGTS under phosphorus-deficient conditions through the eukaryotic pathway via the ER. Simultaneously, phosphatidylcholine and phosphatidylethanolamine, which are similar to DGTS in their zwitterionic properties, are almost completely degraded to release 18.1% cellular phosphorus, and to provide diacylglycerol moieties for a part of DGTS synthesis. This lipid remodeling system that substitutes DGTS for extrachloroplast phospholipids to lower the P-quota operates through the expression induction of the BTA1 gene. Investigation of this lipid remodeling system is necessary in a wide range of lower green plants for a comprehensive understanding of their phosphorus deficiency acclimation strategies.

Topics & Concepts

PhosphatidylethanolamineAlgaeChlorophyceaePhosphatidylcholineBiochemistryBiologyGreen algaeBetaineBotanyLipid metabolismChlorellaPhosphorusCell biologyPhospholipidChemistryChlorophytaMembraneOrganic chemistryLipid metabolism and biosynthesisPhotosynthetic Processes and MechanismsAlgal biology and biofuel production