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Vascular thromboembolic events following COVID‐19 hospital discharge: Incidence and risk factors

Harish Eswaran, Jamie A. Jarmul, Amy W. Shaheen, David Meaux, Tristan Long, Derek Saccoccio, Stephan Moll

2021Research and Practice in Thrombosis and Haemostasis29 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Coronavirus disease 2019 (COVID-19) is associated with high rates of thromboembolic events in hospitalized patients. It remains to be determined if this risk persists following hospital discharge. METHODS: We conducted a retrospective cohort study of outpatients recently hospitalized for COVID-19 to determine the incidence of vascular thromboembolic events within 30 days of discharge. We investigated the risk factors associated with these events, including intensive care admission, age, and anticoagulation. RESULTS: Among 447 patients hospitalized for COVID-19, 2.0% experienced a vascular thromboembolic event within 30 days of discharge. No risk factor variable was significantly associated with an increased risk for these events. CONCLUSIONS: The incidence of vascular thromboembolic events following hospital discharge for COVID-19 is low. These findings suggest against the routine use of postdischarge thromboprophylaxis in patients with COVID-19.

Topics & Concepts

MedicineIncidence (geometry)Coronavirus disease 2019 (COVID-19)Retrospective cohort studyEmergency medicineHospital dischargeRisk factorIntensive care medicineInternal medicineDiseaseInfectious disease (medical specialty)PhysicsOpticsCOVID-19 Clinical Research StudiesVenous Thromboembolism Diagnosis and ManagementCOVID-19 and healthcare impacts