Locked and Loaded: β-Galactosidase Activated Photodynamic Therapy Agent Enables Selective Imaging and Targeted Treatment of Glioblastoma Multiforme Cancer Cells
Toghrul Almammadov, Zübeyir Elmazoğlu, Gizem Atakan Alkan, Dilay Kepil, Güzide Aykent, Safacan Kölemen, Görkem Günbaş
Abstract
marks the first example of a β-gal activatable phototheranostic agent toward effective treatment of glioblastoma.
Topics & Concepts
Photodynamic therapyGlioblastomaCancer researchU87Radiation therapyQuantum yieldChemistryFluorescenceMedicineInternal medicineQuantum mechanicsOrganic chemistryPhysicsNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesCancer Research and Treatments