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Cardiac surgery-associated acute kidney injury: pathophysiology and diagnostic modalities and management

Gontse Leballo, Palesa Motshabi Chakane

2020Cardiovascular journal of South Africa/Cardiovascular journal of Southern Africa21 citationsDOIOpen Access PDF

Abstract

Acute kidney injury is a disease spectrum that can present with from mild renal dysfunction to complete renal failure that would require renal replacement therapy. Cardiac surgery-associated acute kidney injury is a complication that carries a grave disease burden. Risk factors are identified as being either modifiable or non-modifiable. This literature review aims to define the pathophysiology of cardiac surgery-associated acute kidney injury, the current definition and classification of acute kidney injury and the available diagnostic modalities, especially the use of biomarkers.

Topics & Concepts

MedicineAcute kidney injuryPathophysiologyRenal replacement therapyIntensive care medicineKidney diseaseCardiac surgeryComplicationDiseaseModalitiesKidneyInternal medicineSociologySocial scienceAcute Kidney Injury ResearchCardiac Arrest and ResuscitationTrauma, Hemostasis, Coagulopathy, Resuscitation
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