Immunomodulatory zymosan/ι-carrageenan/ agarose hydrogel for targeting M2 to M1 macrophages (antitumoral)
Geetha Venkatachalam, Jayant Giri, Saurav Mallik, Gandarvakottai Senthilkumar Arumugam, Arulmani Manavalan, Vimal Kumar Dewangan, Mukesh Doble, Zhongming Zhao
Abstract
cells per mL) and have a higher swelling (≈250-280%). This study indicates that ZM-based hydrogel could be a potential drug carrier (Rifampicin and Levofloxacin) for targeting tumour-associated macrophages (M2).
Topics & Concepts
AgaroseZymosanCarrageenanChemistryMacrophageWound healingCancer researchBiochemistryImmunologyIn vitroMedicineSeaweed-derived Bioactive CompoundsEchinoderm biology and ecologyHydrogels: synthesis, properties, applications