Reactive oxygen species-scavenging hollow MnO<sub>2</sub> nanozymes as carriers to deliver budesonide for synergistic inflammatory bowel disease therapy
Huiqiang Qiu, Hengtai Gong, Yuheng Bao, Hong Jiang, Weijun Tong
Abstract
carriers and anti-inflammatory drug by blocking the amplification effect of inflammation. In addition, compared with free Bud, the drug delivery system can reduce side effects of Bud and improve its treatment outcome at the same dosage. Therefore, this study provides a new method for the design of highly effective synergistic anti-inflammatory nanomedicines.
Topics & Concepts
Proinflammatory cytokineReactive oxygen speciesChemistryBudesonideInflammatory bowel diseasePharmacologyInflammationDrugBiochemistryImmunologyMedicineDiseasePathologyAsthmaAdvanced Nanomaterials in CatalysisNanoplatforms for cancer theranosticsNanocluster Synthesis and Applications