Extracellular Vesicle Biogenesis and Functions in Gram-Positive Bacteria
Paul Briaud, Ronan K. Carroll
Abstract
Extracellular vesicles (EVs) are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells. Bacterial membrane vesicles were discovered over 60 years ago and have been extensively studied in Gram-negative bacteria. During their production, EVs are loaded with proteins, nucleic acids, and various compounds that are subsequently released into the environment. Depending on the packaged cargo, EVs have a broad spectrum of action and are involved in pathogenesis, antibiotic resistance, nutrient uptake, and nucleic acid transfer.
Topics & Concepts
BiologyBacteriaBiogenesisNucleic acidVesicleExtracellularExtracellular vesicleMicrobiologyGram-negative bacteriaBiochemistryBacterial outer membraneMicrovesiclesCell biologyMembraneEscherichia coliGeneticsmicroRNAGeneBacterial Infections and VaccinesExtracellular vesicles in diseaseInfective Endocarditis Diagnosis and Management