Coronary flow reserve: a versatile tool for interrogating pathophysiology, and a reliable marker of cardiovascular outcomes and mortality
Viviany R. Taqueti
Abstract
(A) Coronary flow reserve (CFR) is a quantitative measure of myocardial ischaemia that integrates the haemodynamic contribution of the large and small coronary vessels to myocardial tissue perfusion. CFR is a sensitive marker of cardiac ischaemia beyond inducible regional wall motion abnormalities or visible perfusion defects. (B) The value proposition of coronary blood flow measurement for personalized imaging of patients with coronary heart disease. CAD, coronary artery disease.
Topics & Concepts
MedicineCardiologyCoronary flow reserveCoronary artery diseaseInternal medicinePerfusionBlood flowPathophysiologyFractional flow reservePerfusion scanningHemodynamicsIschemiaCoronary circulationMyocardial perfusion imagingMyocardial infarctionCoronary angiographyCardiac Imaging and DiagnosticsCoronary Interventions and DiagnosticsAdvanced MRI Techniques and Applications