Toyoncin, a Novel Leaderless Bacteriocin That Is Produced by Bacillus toyonensis XIN-YC13 and Specifically Targets B. cereus and Listeria monocytogenes
Juanjuan Wang, Haitao Xu, Shu Liu, Baolong Song, Hualin Liu, Feng Li, Shulin Deng, Guangli Wang, Huawei Zeng, Xin Zeng, Dayong Xu, Biao Zhang, Bingyue Xin
Abstract
We identified a novel leaderless bacteriocin, toyoncin, produced by B. toyonensis XIN-YC13. Toyoncin shows good pH and heat stability, and it has specific antimicrobial activity against B. cereus and L. monocytogenes (two important foodborne pathogens), likely by destroying their cell membrane integrity. Toyoncin inhibited the outgrowth of B. cereus spores and effectively inhibited or eliminated B. cereus and L. monocytogenes in a milk model system. These results indicate the potential of toyoncin as a food preservative.
Topics & Concepts
Listeria monocytogenesBacillus cereusBacteriocinCereusMicrobiologyListeriaAntimicrobialBiologyBacteriaChemistryGeneticsProbiotics and Fermented FoodsBacteriophages and microbial interactionsMicrobial Inactivation Methods