Facile synthesis of a hydrazone-based zinc(<scp>ii</scp>) complex for ferroptosis-augmented sonodynamic therapy
Dan Li, Minghui Fan, Haobing Wang, Yongjie Zhu, Bole Yu, Pingyu Zhang, Huaiyi Huang
Abstract
studies further demonstrate that ZnAMTC exhibits efficient tumor growth inhibition under US irradiation and has good biosafety. This work provides useful insights into the design of first-row transition metal complexes for SDT application.
Topics & Concepts
HydrazoneSonodynamic therapyZincChemistryCombinatorial chemistryOrganic chemistryPhotodynamic therapyNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryLanthanide and Transition Metal Complexes