Different directions for <i>retro</i>‐<i>inverso</i> peptides
George W. Preston
Abstract
Retro-inverso peptides are reversed sequences of mirror-image amino acid residues. Synthetic molecules of this type have long been considered potential mimics of functional peptides. This Peptide Highlights article examines some recent applications of the retro-inverso transformation at the interface of peptide chemistry and medicine.
Topics & Concepts
PeptideChemistryStereochemistryAmino acid residueAmino acidBiochemistryPeptide sequenceCombinatorial chemistryMoleculeTransformation (genetics)Computational biologyBiologyOrganic chemistryGeneChemical Synthesis and AnalysisRNA and protein synthesis mechanismsClick Chemistry and Applications