A Review of Optical Imaging Technologies for Microfluidics
Pan Zhou, Haipeng He, Hanbin Ma, Shurong Wang, Siyi Hu
Abstract
Microfluidics can precisely control and manipulate micro-scale fluids, and are also known as lab-on-a-chip or micro total analysis systems. Microfluidics have huge application potential in biology, chemistry, and medicine, among other fields. Coupled with a suitable detection system, the detection and analysis of small-volume and low-concentration samples can be completed. This paper reviews an optical imaging system combined with microfluidics, including bright-field microscopy, chemiluminescence imaging, spectrum-based microscopy imaging, and fluorescence-based microscopy imaging. At the end of the article, we summarize the advantages and disadvantages of each imaging technology.
Topics & Concepts
MicrofluidicsNanotechnologyMicroscopyOptical imagingFluorescence-lifetime imaging microscopyMicrofluidic chipImaging technologyFluorescence microscopeMaterials scienceComputer scienceFluorescenceOpticsPhysicsMedicineRadiologyInnovative Microfluidic and Catalytic Techniques InnovationMicrofluidic and Capillary Electrophoresis ApplicationsBiosensors and Analytical Detection