Inhibition of the DSB repair protein RAD51 potentiates the cytotoxic efficacy of doxorubicin via promoting apoptosis-related death pathways
Leonie Schürmann, Lena Schumacher, Katharina Roquette, Anamaria Brozović, Gerhard Fritz
Topics & Concepts
CytotoxicityDoxorubicinCancer researchTopoisomeraseApoptosisCytotoxic T cellDNA damageOxaliplatinDNA repairPharmacologyColorectal cancerBiologyMedicineIn vitroChemotherapyCancerDNAInternal medicineBiochemistryDNA Repair MechanismsCancer therapeutics and mechanismsGenetic factors in colorectal cancer