Metal–organic framework-interfaced ELISA probe enables ultrasensitive detection of extracellular vesicle biomarkers
Jingzhu Shi, Sharat Chandra Barman, Shibo Cheng, Yong Zeng
Abstract
-fold improvement compared to that obtained with the standard ELISA. Moreover, the heightened sensitivity of this technique renders it particularly suitable for diagnosing breast cancer, thus presenting a promising tool for the early detection of the disease in clinical settings.
Topics & Concepts
Extracellular vesiclesChemistryExtracellular vesicleChromatographyEnzymeBiochemistryMicrovesiclesBiologyCell biologymicroRNAGeneAdvanced biosensing and bioanalysis techniquesElectrochemical Analysis and ApplicationsAdvanced Nanomaterials in Catalysis