Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels–Alderase
Michio Sato, Shinji Kishimoto, Mamoru Yokoyama, Cooper S. Jamieson, Kazuto Narita, Naoya Maeda, Kodai Hara, Hiroshi Hashimoto, Yuta Tsunematsu, K. N. Houk, Yi Tang, Kenji Watanabe
Topics & Concepts
MutagenesisStereochemistryChemistryKinetic resolutionEnzymeCycloadditionNatural productCatalysisAdductReversionMetaboliteBicyclic moleculeMutantCombinatorial chemistryComputational biologyBiochemistryBiologyEnantioselective synthesisGenePhenotypeOrganic chemistryMicrobial Natural Products and BiosynthesisPlant biochemistry and biosynthesisPhotosynthetic Processes and Mechanisms