Litcius/Paper detail

Discovery of a highly selective BChE inhibitor with concomitant anti-neuroinflammatory activity for treating Alzheimer's disease

Yarong Zhao, Kun Wu, Wei Luo, Yuting Zhao, Jing Zeng, Junbo Wu, Changlei Yang, Meiling Yang, Jia‐Bao Liu, Zhengwen Lei, Peng Xue, Zhen Wang

2025European Journal of Medicinal Chemistry9 citationsDOI

Topics & Concepts

ChemistryPharmacologyConcomitantEnzyme inhibitorButyrylcholinesteraseAlzheimer's diseaseNeuroinflammationDiseaseAchéAcetylcholinesteraseEnzymeBiochemistryInternal medicineMedicineCholinesterase and Neurodegenerative DiseasesTryptophan and brain disordersComputational Drug Discovery Methods