Molecular Mechanisms in the Transformation from Indolent to Aggressive B Cell Malignancies
Nawar Maher, Samir Mouhssine, Bassam Francis Matti, A Alwan, Gianluca Gaïdano
Abstract
Histological transformation (HT) into aggressive lymphoma is a turning point in a significant fraction of patients affected by indolent lymphoproliferative neoplasms, namely, chronic lymphocytic leukemia (CLL), follicular lymphoma (FL), marginal zone lymphomas (MZLs), and lymphoplasmacytic lymphoma (LPL) [...].
Topics & Concepts
Chronic lymphocytic leukemiaLymphoplasmacytic LymphomaHairy cell leukemiaFollicular lymphomaLymphomaMarginal zoneMedicinePathologyLymphoproliferative disordersCancer researchSplenic marginal zone lymphomaAggressive lymphomaLeukemiaB cellOncologyWaldenstrom macroglobulinemiaInternal medicineImmunologyRituximabAntibodyChronic Lymphocytic Leukemia ResearchLymphoma Diagnosis and TreatmentViral-associated cancers and disorders