Rational Synthesis of Imine-Linked Fluorescent Covalent Organic Frameworks with Different p<i>K</i><sub>a</sub> for pH Sensing In Vitro and In Vivo
Fang Yuan, Yujing Kong, Jia You, Cuiling Zhang, Yuezhong Xian
Abstract
was further employed as a good candidate for pH imaging in tumor cells and zebrafish. The as-constructed environment-sensitive fluorescent COFs have greatly expanded the applications of COFs in the biological area.
Topics & Concepts
FluorescenceBiocompatibilityImineMaterials scienceCovalent bondCovalent organic frameworkNanotechnologyCombinatorial chemistryIn vivoBiophysicsChemistryOrganic chemistryBiologyQuantum mechanicsMetallurgyCatalysisBiotechnologyPhysicsCovalent Organic Framework ApplicationsLuminescence and Fluorescent MaterialsMetal-Organic Frameworks: Synthesis and Applications