Early precursor T-cell acute lymphoblastic leukemia: current paradigms and evolving concepts
Omar Castañeda Puglianini, Nikolaos Papadantonakis
Abstract
Early precursor T cell-acute lymphoblastic leukemia (ETP-ALL) is a rare entity characterized by chemo-resistance and a paucity of data regarding optimal management. We review here the literature regarding the management of ETP-ALL and focus on the recent, emerging data, regarding the potential role of molecularly targeted approaches with a focus on venetoclax.
Topics & Concepts
MedicineVenetoclaxLymphoblastic LeukemiaLeukemiaCancer researchBioinformaticsOncologyImmunologyChronic lymphocytic leukemiaBiologyAcute Lymphoblastic Leukemia researchCAR-T cell therapy researchChronic Myeloid Leukemia Treatments