Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France
Christophe Rodriguez, Meriadeg Ar Gouilh, Nicolas Weiss, Sébastian Ströer, Karima Mokhtari, Danielle Seilhean, Bertrand Mathon, Vanessa Démontant, Mélissa N’Debi, Guillaume Gricourt, Paul‐Louis Woerther, Jean–Michel Pawlotsky, Karl Stéfic, Julien Marlet, Pierre‐François Dequin, Antoine Guillon, Valérie Pourcher, David Boutolleau, Astrid Vabret, Sonia Burrel
Abstract
W e report a fatal case of measles inclusion-body encephalitis in a 28-year-old woman from Romania living in France who had untreated AIDS. She was initially admitted to the hospital on September 22, 2018 (day 0), for afebrile generalized motor seizure that began focally in the right lower limb. Results of magnetic resonance imaging (MRI) were initially unremarkable, but electroencephalogram (EEG) results showed slight abnormalities related to slow frontal activity. The patient recovered fully and was discharged with antiepileptic therapy. Of note, the patient had stopped antiretroviral therapy (ART) 1 year earlier and declined to restart therapy after this hospital admission.