Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics
Jean Morrison, Nicholas Knoblauch, Joseph Marcus, Matthew Stephens, Xin He
Topics & Concepts
Mendelian randomizationPleiotropyBiologyFalse positive paradoxGenome-wide association studyUncorrelatedMendelian inheritanceGeneticsCausal inferenceComputational biologyStatisticsGenetic variantsSingle-nucleotide polymorphismMathematicsPhenotypeGeneGenotypeGenetic Associations and EpidemiologyGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals