High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis
Laura Bouchareychas, Phat Duong, Tuan Anh Phu, Eric Alsop, Bessie Meechoovet, Rebecca Reiman, Martin Ng, Ryō Yamamoto, Hiromitsu Nakauchi, Warren J. Gasper, Kendall Van Keuren‐Jensen, Robert L. Raffaı̈
Abstract
control. Together, our findings show that EVs serve to communicate detrimental properties of hyperglycemia to accelerate atherosclerosis in diabetes.
Topics & Concepts
MicrovesiclesHaematopoiesisMacrophageMyeloidChemistryCell biologyApoptosisGlycolysisCancer researchBiologyBiochemistrymicroRNAMetabolismStem cellIn vitroGeneExtracellular vesicles in diseaseMicroRNA in disease regulationAtherosclerosis and Cardiovascular Diseases