Imaging therapeutic peptide transport across intestinal barriers
Jannik B. Larsen, Nayere Taebnia, Alireza Dolatshahi‐Pirouz, Anne Z. Eriksen, Claudia U. Hjørringgaard, Kasper Kristensen, Nanna Wichmann Larsen, Niels B. Larsen, Rodolphe Marie, Ann-Kathrin Mündler, Ladan Parhamifar, Andrew J. Urquhart, Arjen Weller, Kim I. Mortensen, Henrik Flyvbjerg, Thomas L. Andresen
Abstract
Understanding how pharmaceutical peptides transport across the intestinal barrier could increase their bio-availability. To this end, fluorescence imaging offers a unique combination of spatiotemporal resolution and compatibility with living systems.
Topics & Concepts
PeptideChemistryBiochemistryRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryDrug Transport and Resistance Mechanisms