Multi-omics study of silicosis reveals the potential therapeutic targets PGD<sub>2</sub> and TXA<sub>2</sub>
Junling Pang, Xianmei Qi, Ya Luo, Xiaona Li, Ting Shu, Baicun Li, Meiyue Song, Ying Liu, Dong Wei, Jingyu Chen, Jing Wang, Chen Wang
Abstract
in the progression of silicosis. By blocking the receptors of these two prostanoids, Ramatroban may be a novel potential therapeutic drug to inhibit the progression of silicosis.
Topics & Concepts
SilicosisMedicinePharmacologyInflammationLungOccupational lung diseaseFibrosisLung transplantationThromboxane A2ImmunologyPathologyReceptorInternal medicineInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisMedical Imaging and Pathology StudiesSarcoidosis and Beryllium Toxicity Research