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Synthetic antiprotozoal thiazolide drug induced apoptosis in colorectal cancer cells: implications of IL-6/JAK2/STAT3 and p53/caspases-dependent signaling pathways based on molecular docking and in vitro study

Mohamed A. Tantawy, Nagla A. El-Sherbeeny, Nawal Helmi, Reem S. Alazragi, Neveen A. Salem, Samah M. Elaidy

2020Molecular and Cellular Biochemistry37 citationsDOI

Topics & Concepts

CaspaseApoptosisCancer researchBiologyPharmacologyProgrammed cell deathBiochemistryCytokine Signaling Pathways and InteractionsCancer Mechanisms and TherapySynthesis and biological activity
Synthetic antiprotozoal thiazolide drug induced apoptosis in colorectal cancer cells: implications of IL-6/JAK2/STAT3 and p53/caspases-dependent signaling pathways based on molecular docking and in vitro study | Litcius