Therapeutic efficacy of PD1/PDL1 blockade in B16 melanoma is greatly enhanced by immunization with dendritic cell-targeting lentiviral vector and protein vaccine
Tina C. Albershardt, Andrea Parsons, Rebecca Susan Reeves, Patrick Flynn, D. J. Campbell, Jan ter Meulen, Peter Berglund
Topics & Concepts
Immune systemImmune checkpointAntigenBlockadeImmunologyCancer researchImmunotherapyImmunizationViral vectorTumor antigenMedicineMelanomaHeterologousCancer immunotherapyT cellBiologyVirologyRecombinant DNAInternal medicineReceptorGeneBiochemistryCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCAR-T cell therapy research