Insights into circular RNAs: their biogenesis, detection, and emerging role in cardiovascular disease
Zoë Ward, John F. Pearson, Sebastian Schmeier, Vicky A. Cameron, Anna P. Pilbrow
Abstract
identification, functional prediction, and validation of circRNAs. However, few cardiovascular circRNA studies have utilized these tools. This review summarizes current knowledge of circRNA biogenesis, bioinformatic detection tools and the emerging role of circRNAs in cardiovascular disease.
Topics & Concepts
BiologyComputational biologyBiogenesisCircular RNAIdentification (biology)Mechanism (biology)microRNATranscriptomeBioinformaticsGeneticsGeneGene expressionPhilosophyEpistemologyBotanyCircular RNAs in diseasesMicroRNA in disease regulationCancer-related molecular mechanisms research