Recent Application of Chiral Aryliodine Based on the 2-Iodoresorcinol Core in Asymmetric Catalysis
Yang Wang, Zheng‐Guang Wu, Bing Yang, Xin‐Xing Wu
Abstract
Abstract Chiral iodoarenes have been steadily increasing in importance in recent years, especially in enantioselective synthesis and catalysis. Since the development of the concept of chiral iodine(I/III) catalysis, the use of various chiral aryliodine frameworks has been explored in this area. This short review gives an overview of the use of chiral hypervalent iodine(I/III) reagents based on the 2-iodoresorcinol core with two attached two lactic side chains bearing ester or amide groups for the catalytic enantioselective dearomatization of phenol compounds, asymmetric oxidation of alkenes, and enantioselective α-functionalization of carbonyl compounds highlighting the excellent reactivities in terms of yield and enantioselectivity. 1 Introduction 2 Enantioselective Dearomatization of Phenol Derivatives 3 Asymmetric Oxidation of Alkenes 4 Enantioselective α-Functionalization of Carbonyl Compounds 5 Conclusion and Outlook