Sinoorbital Mucormycosis Associated with Corticosteroid Therapy in COVID-19 Infection
Zeinab Mehrabi, Maryam Salimi, Kianoush Niknam, Farzaneh Mohammadi, Hesan Jelodari Mamaghani, Mohammad Reza Sasani, Mohammad Javad Ashraf, Amirhossein Salimi, Mohammad Hassan Zahedroozegar, Zohreh Erfani
Abstract
Background. Mucormycosis is a rare and invasive fungal infection, affecting almost exclusively immunocompromised individuals. Immunosuppressive effects of corticosteroids which are widely prescribed in COVID-19 patients might be a predisposing factor for opportunistic infections even though the other factors should also be considered. Case Presentation. A middle-aged man without any significant past medical history was admitted to the hospital due to a severe COVID-19 infection. He received a high dose of corticosteroids as a part of the treatment. Five days after discharge, he presents with a headache and fever. Eventually, orbital mucormycosis was diagnosed for him and he was treated with antifungal medications. Conclusion. Opportunistic infections should be considered during the current pandemic of COVID-19, during which corticosteroids are widely prescribed.