Enhanced anti-tumor efficacy by inhibiting HIF-1α to reprogram TAMs<i>via</i>core-satellite upconverting nanoparticles with curcumin mediated photodynamic therapy
Lijun Zhang, Rui Huang, Yiwen Shen, Jie Liu, Ye Wu, Jinmei Jin, Hong Zhang, Yun Sun, Hongzhuan Chen, Xin Luan
Abstract
T cells' infiltration. Our data highlight the novel application of CSNPs-embedded Cur as a difunctional photosensitizer to enhance the anti-tumor efficacy of PDT.
Topics & Concepts
CurcuminPhotodynamic therapyCancer researchChemistryTumor microenvironmentSatelliteTumor cellsMedicineBiochemistryOrganic chemistryEngineeringAerospace engineeringNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesCancer, Hypoxia, and Metabolism