Cryoprotectant optimization for enhanced stability and transfection efficiency of pDNA-loaded ionizable lipid nanoparticles
Heloísa Athaydes Seabra Ferreira, Sérgio Scalzo, Kevin Kelton Santos de Faria, Gabriel Henrique Costa da Silva, Marco Túllio Rodrigues Alves, Anderson Oliveira Lobo, Pedro Pires Goulart Guimarães
Topics & Concepts
CryoprotectantTrehaloseNucleic acidTransfectionChemistryFreeze-dryingGlycerolCryopreservationBiochemistryBiophysicsCell biologyChromatographyBiologyGeneEmbryoRNA Interference and Gene DeliveryViral gastroenteritis research and epidemiologyVirus-based gene therapy research