Electrochemical Benzylic C(sp<sup>3</sup>)-H Imidation Enabled by Benzoic Acid Derived Radicals
Peng Qian, Dan Zhu, Xiaoli Wang, Qi Sun, Sheng Zhang
Abstract
)-H imidation by virtue of the in situ generated oxygen-centered radicals (OCRs). The electrochemical imidation provides a complementary approach to giving distinct imide products compared with previous acyloxylation products. This protocol exhibits good site selectivity and broad substrate generality. Moreover, the utility of the OCR-mediated protocol was extended to the electrochemical oxidation of silane, and its robustness was also highlighted by the imidation of complex substrates, which would otherwise be inaccessible for previous approaches. A plausible reaction mechanism was proposed to rationalize the experimental observations.
Topics & Concepts
ChemistryRadicalElectrochemistryImideBenzoic acidRobustness (evolution)Combinatorial chemistrySubstrate (aquarium)Organic chemistryElectrodePhysical chemistryBiochemistryGeneOceanographyGeologyCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsCO2 Reduction Techniques and Catalysts