Pd-catalyzed access to mono- and di-fluoroallylic amines from primary anilines
Xingben Wang, Frédéric W. Patureau
Abstract
zeroth order in the aniline coupling partner. The newly produced fluoroallylic motifs should find important applications in synthetic as well as medicinal chemistry and stimulate the further development of coupling methods based on strained cyclic building blocks.
Topics & Concepts
AnilineCatalysisPrimary (astronomy)Substrate (aquarium)Combinatorial chemistryChemistryCoupling (piping)Organic chemistryMaterials sciencePhysicsMetallurgyOceanographyAstronomyGeologyFluorine in Organic ChemistryCyclopropane Reaction MechanismsCatalytic Cross-Coupling Reactions