Atomic-scale characterization of mature HIV-1 capsid stabilization by inositol hexakisphosphate (IP <sub>6</sub> )
Alvin Yu, Elizabeth Lee, Jaehyeok Jin, Gregory A. Voth
Abstract
All-atom simulations reveal the molecular mechanisms of inositol hexakisphosphate binding to HIV capsids.
Topics & Concepts
CapsidCharacterization (materials science)Human immunodeficiency virus (HIV)Atomic unitsInositolScale (ratio)Computational biologyBiophysicsChemistryVirologyBiologyNanotechnologyPhysicsMaterials scienceBiochemistryVirusReceptorQuantum mechanicsHIV Research and TreatmentHIV/AIDS drug development and treatmentEnzyme Structure and Function