Litcius/Paper detail

A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy

Jia-Luo Huang, Leiming Wu, Shuqi Wu, Fang-Yu Yuan, Han‐Zhuang Weng, Dong Huang, Lu Gan, Shuo-Bin Chen, Gui‐Hua Tang, Sheng Yin

2025Nature Chemical Biology5 citationsDOI

Topics & Concepts

AutophagySmall moleculeCancer researchChemistryInducerEffectorCell biologyLung cancerDownregulation and upregulationProgrammed cell deathATPaseProtein subunitCancerCell growthBiologyULK1CellCytokineSignal transductionApoptosisLungCell culturePharmacologyAutophagy in Disease and TherapyUbiquitin and proteasome pathwaysSignaling Pathways in Disease
A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy | Litcius