An Integrated Temperature-Feedback Photothermal Therapy Platform Based on Dual-Functional Rare Earth-Doped NaSrGd(MoO<sub>4</sub>)<sub>3</sub> Phosphors
Ping Zhang, Xufang Wang, Shilong Zhao, Xiuli Wang, Ruoshan Lei, Lihui Huang, Shiqing Xu
Abstract
Nd 3+ doped and Er 3+ /Yb 3+ codoped NaSrGd(MoO 4 ) 3 (NSGM) phosphors were synthesized and used to build an integrated temperature-feedback photothermal therapy platform. Intense green upconversion emissions were observed in Er 3+ /Yb 3+ -codoped NSGM phosphors and used to construct an all-fiber temperature sensing probe. The temperature dependent fluorescence intensity ratio (FIR) calibration curve was established and the absolute temperature sensitivity S a reached the maximum value of 0.013 K –1 at 423 K. The photothermal conversion performance of NSGM:Nd 3+ phosphors could be easily modified by altering Nd 3+ doping concentration and 808 nm laser irradiation power. An integrated all-fiber photothermal temperature measurement platform was built and the temperature measurement error was smaller than ±1 K, which could simultaneously achieve photothermal conversion and temperature measurement in narrow spaces and was expected to be used in local photothermal therapy applications.