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Inhibitors of Keap1-Nrf2 protein-protein interaction reduce estrogen responsive gene expression and oxidative stress in estrogen receptor-positive breast cancer

Tingying Xie, Husam Zahid, Ahmed R. Ali, Ryan Joyce, Ge Yang, Cassandra Winz, Yicong Le, Renping Zhou, Philip Furmanski, Longqin Hu, Nanjoo Suh

2023Toxicology and Applied Pharmacology15 citationsDOIOpen Access PDF

Topics & Concepts

KEAP1Estrogen receptorOxidative stressEstrogenEstrogen receptor alphaUbiquitinChemistryCancer researchPharmacologyBreast cancerCancerBiologyGeneBiochemistryTranscription factorEndocrinologyGeneticsGenomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms
Inhibitors of Keap1-Nrf2 protein-protein interaction reduce estrogen responsive gene expression and oxidative stress in estrogen receptor-positive breast cancer | Litcius