Photoredox catalyzed C–H trifluoroethylamination of heteroarenes
Juan Wang, Shuai Liu, Yangen Huang, Xiu‐Hua Xu, Feng‐Ling Qing
Abstract
-trifluoroethyl hydroxylamine reagents was achieved under photoredox catalyzed conditions. In the presence of an iridium(III) photoredox catalyst, a variety of heteroarenes, such as indoles, benzofurans, and benzothiophenes, were smoothly converted to the trifluoroethylaminated products in moderate to high yields and with excellent regioselectivity.
Topics & Concepts
RegioselectivityPhotoredox catalysisIridiumReagentHydroxylamineCatalysisChemistryCombinatorial chemistryOrganic chemistryPhotocatalysisFluorine in Organic ChemistryCatalytic C–H Functionalization MethodsRadical Photochemical Reactions