HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer
Katsuhiro Yoshimura, Gengyi Zou, Yibo Fan, Kohei Yamashita, Lingzhi Wang, Jingjing Wu, Ruiping Wang, Shan Shao, Ailing W. Scott, Jiankang Jin, Melissa Pool Pizzi, Xiaodan Yao, Calena-Abel Brown, Linghua Wang, Qiong Gan, Rebecca Waters, Feng Yin, Shumei Song, Shilpa S. Dhar, Jaffer A. Ajani
Topics & Concepts
Cancer researchImmune systemHsp90CancerGrowth inhibitionSignal transductionBiologyChemistryApoptosisMedicineImmunologyInternal medicineCell biologyHeat shock proteinBiochemistryGeneHippo pathway signaling and YAP/TAZHeat shock proteins researchToxin Mechanisms and Immunotoxins