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Predictors of Short-Term Outcome of Kasai Portoenterostomy for Biliary Atresia in Infants: a Single-Center Study

Noha Adel Yassin, Gamal Eltagy, Omar Nagy Abdelhakeem, Noha Asem, Hanaa El‐Karaksy

2020Pediatric Gastroenterology Hepatology & Nutrition17 citationsDOIOpen Access PDF

Abstract

PURPOSE: The outcome predictors of Kasai portoenterostomy (KPE) for biliary atresia (BA) are controversial. This study aimed to identify possible short-term outcome predictors of KPE for BA in infants. METHODS: This retrospective study included infants with BA who underwent KPE between January 2015 and December 2017 and were followed up for at least 6 months after surgery at the Pediatric Hepatology Unit, Cairo University Pediatric Hospital, Egypt. The short-term outcome was jaundice clearance within 6 months following surgery. All data were compared between the jaundice free group and those with persistent jaundice to identify the predictors of jaundice clearance. RESULTS: =0.008). CONCLUSION: Jaundice clearance after KPE for BA can be predicted using preoperative AST and presence of bile plugs in liver biopsy.

Topics & Concepts

MedicineJaundiceBiliary atresiaHepatologyGastroenterologyInternal medicineLiver biopsyRetrospective cohort studyConfidence intervalSingle CenterSurgeryBiopsyLiver transplantationTransplantationPediatric Hepatobiliary Diseases and TreatmentsGallbladder and Bile Duct DisordersNeonatal Health and Biochemistry