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Organocatalysis Meets Hydrocarbon Oxyfunctionalization: the Role of <i>N</i>‐Hydroxyimides

Marta A. Andrade, Luísa M. D. R. S. Martins

2021European Journal of Organic Chemistry28 citationsDOI

Abstract

Abstract The merging of organocatalysis and C−H bond oxyfunctionalization has demonstrated to be a powerful approach towards the development of new efficient and selective synthetic protocols. Both research areas have witnessed a tremendous growth over the past two decades, with a high number of studies mainly reporting the use of N ‐hydroxyphthalimide (NHPI) and related compounds in the selective oxyfunctionalization of hydrocarbons. Additionally, heterogeneous NHPI‐based systems can provide a green and sustainable perspective for oxidation reactions. Nevertheless, reports related to this latter approach are still scarce and need further scouting in terms of types of supports used. This short review accounts for relevant contributions from 2010 onwards on the use of NHPI‐based systems for hydrocarbon oxyfunctionalization.

Topics & Concepts

OrganocatalysisChemistryHydrocarbonPerspective (graphical)Organic chemistryBiochemical engineeringCombinatorial chemistryEnantioselective synthesisCatalysisComputer scienceArtificial intelligenceEngineeringCatalytic C–H Functionalization MethodsOxidative Organic Chemistry ReactionsChemical Synthesis and Reactions
Organocatalysis Meets Hydrocarbon Oxyfunctionalization: the Role of <i>N</i>‐Hydroxyimides | Litcius